(Senior) Director, FP&A at Orca Bio – Menlo Park, California

Position Summary: Reporting into our CFO & Head of Strategy, the (Senior) Director, FP&A (depending on experience) will lead financial planning, forecasting, and reporting at Orca Bio, building upon our existing FP&A processes to scale into a commercial-ready function. This individual will serve as the functional leader for FP&A and is a highly visible, hands-on leader responsible for evolving our structure, processes, and financial rigor in a fast-growing, pre-commercial biotech environment. The role partners closely with Clinical Development, R&D, Manufacturing Operations, Medical Affairs, and Commercial leadership to drive budgeting, forecasting, and decision support across the organization.

This position will focus on core FP&A responsibilities (budgeting, forecasting, and operational finance), while partnering with leadership and adjacent functions on longer-term strategic and valuation-related initiatives.

• Own company-wide budgeting, forecasting, and monthly/quarterly actuals analysis, including variance analysis vs. plan
• Own the company’s financial forecast and ensure accuracy, consistency, and alignment across functions
• Enhance existing FP&A processes, reporting cadence, and financial infrastructure to support commercial launch
• Lead financial planning across R&D, Clinical, Manufacturing, and Commercial functions
• Own commercial financial planning, including revenue forecasts, patient flow models, and demand assumptions, in close partnership with Commercial leadership
• Partner with Accounting to align on cost visibility, including manufacturing economics and COGS drivers
• Develop long-range financial models to support strategic planning, investment decisions, and Board-level discussions
• Partner with functional leaders to track performance against plan and drive accountability for financial targets
• Translate financial results into clear, actionable insights for executive leadership

• Bachelor’s degree in Finance, Accounting, Economics, or related field (MBA preferred)
• 12+ years of progressive FP&A experience, including leadership experience in a biotech or life sciences company, preferably with commercial launch experience
• Demonstrated experience building or scaling FP&A processes in a high-growth, small to mid-sized organization
• Experience partnering with commercial organizations, including revenue forecasting and launch planning
• Experience supporting clinical organizations, including clinical development forecasting and portfolio planning
• Familiarity with manufacturing environments; in-house manufacturing experience preferred
• Advanced financial modeling and analytical skills, with ability to translate data into business insights
• Prior experience in smaller or mid-sized biotech environments preferred; candidates should be comfortable operating with limited structure and high ownership