Research Associate in Portland, Oregon at Oregon Health & Science University
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Job Description
US-OR-Portland
Requisition ID: 2026-39099
Position Category: Research
Job Type: Research
Position Type: Regular Full-Time
Posting Department: Center for Embryonic Cell and Gene Therapy
Posting Salary Range: $50,814 - $84,697 per year, with offer based on experience, education and internal equity
Posting FTE: 1.00
Posting Schedule: Monday - Friday, some weekends/holidays shifts
Posting Hours: 8:00am - 5:00pm, some late nights, weekends, holiday coverage required
HR Mission: Research
Drug Testable: No
LinkedIn Job Code: LI-LP1
Department Overview
This position contributes to ongoing basic and translational research programs within the Center for Embryonic Cell and Gene Therapy (CECGT). http://www.ohsu.edu/xd/research/centers-institutes/embryonic-cell-gene-therapy-center/
The successful candidate will perform a broad range of scientific and operational duties under minimal supervision, requiring a high degree of independence, flexibility, sound judgment, and specialized expertise in cell and gene therapy.
The role involves regular interaction with internal and external collaborators and requires a high level of accuracy, efficiency, and professionalism.
Function/Duties of PositionResearch – Cell Culture and Animal Studies
- Prepare culture media, buffers, and reagents in accordance with established protocols and quality standards.
- Establish and maintain primary cell cultures.
- Derive, culture, and maintain embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) lines.
- Perform animal-based research procedures, including collection of gametes, embryos, and tissues.
- Support mouse colony management, including routine husbandry, genotyping, injections, and weekend coverage as needed.
- Coordinate animal experiments with project leaders; assist with preparation and review of IACUC protocols, ensure regulatory compliance, and maintain accurate records for animal tracking and breeding.
Research – Molecular Biology and Sequencing
- Perform and optimize a range of molecular biology techniques, including DNA/RNA extraction, library preparation, PCR and ARMS-qPCR, pyrosequencing, Sanger sequencing, and next-generation sequencing (e.g., MiSeq, AmpliSeq).
- Conduct downstream assays such as immunocytochemistry, karyotyping, and other relevant analytical techniques as required.
- Prepare, run, and analyze agarose and/or polyacrylamide gels, including sample loading, electrophoresis, and imaging.
Research – Data Collection/Data Analysis/Record Keeping
- Collect, organize, and manage scientific data relevant to ongoing research projects, including database queries and literature searches as needed.
- Maintain the accuracy, integrity, and security of CECGT databases and research records.
- Contribute to the design, planning, and execution of experiments.
Report Preparation
- Prepare reports containing analytical, descriptive, and evaluative content that will be submitted for publication, grant applications, progress reports, presentations at national and international meetings, etc.
- Prepare abstracts for submission to conferences in national and international locations.
- Assist in the preparation of manuscripts, reports, and regulatory documents, including animal research protocols.
Administrative Laboratory Responsibilities
- Oversee and support day-to-day laboratory operations, including routine equipment maintenance and coordination of service/repairs.
- Procure laboratory reagents, consumables, and equipment; manage inventory and ensure timely restocking.
- Maintain organization and readiness of laboratory and cell culture facilities, including supply stocking and space management.
- Support laboratory cleaning schedules, including autoclaving, sterilization, and decontamination procedures in compliance with safety standards.
- Manage purchasing workflows, including P-card transactions, purchase orders, and billing documentation.
- Perform general laboratory upkeep to ensure a clean, safe, and well-functioning research environment.
- Assist with budget tracking, purchasing coordination, and obtaining equipment quotes.
Other duties as assigned.
Required Qualifications
- Master's Degree in relevant field AND 3 years of relevant experience; OR
- Bachelor's Degree in relevant field AND 5 years of relevant experience.
AALAS (American Association for Laboratory Animal Science) certification or willingness to obtain certification.
Knowledge, Skills, and Abilities
- Strong knowledge of mammalian embryology, stem cell biology and mitochondrial.
- Expertise in NGS workflows, including library preparation and sequencing analysis.
- Ability to work effectively in a collaborative academic research environment.
- Commitment to fostering and supporting diverse study populations.
- Highly organized with strong attention to detail.
- Self-motivated with the ability to work independently and manage multiple priorities.
- Demonstrates integrity, professionalism, and a willingness to learn.
Preferred Qualifications
- Advanced degree (M.S. or Ph.D.) in a related field.
- Experience working in academic or translational research environments.
- Hands-on laboratory experience with mouse and human gamete and embryo research, sequencing technologies and stem cell culture.
Additional Details
Standard schedule: Monday–Friday, typically 8:00am - 5:00pm or 7:00am - 4:00pm.
Participation in weekend, evening, and holiday on-call rotations for laboratory and animal-related duties as needed.
Primarily an on-site position with limited telework as approved by the supervisor.
Regular exposure to human, mouse, and non-human primate tissues and biological fluids.
Responsibilities include tissue and fluid collection in accordance with study protocols; training will be provided for proper handling and safety procedures.