Scientist I in Lexington, Kentucky at University of Kentucky

None

Standing for long periods of time

Day shift. Some weekends may be required.

The Plattner lab studies the development and progression of cancer as well as how cancer develops resistance to current therapies.

Examples of publications from the laboratory can be found at Nat Comm (2020) 11:5463; and Cancers (2023) 15(3), 954. The lab is currently seeking an individual to study how pediatric brain cancers develop resistance to targeted therapy (BRAF, MEK inhibitors), a project that will be funded in July, 2026.

The applicant will be expected to work independently and publish 1st author publications working collaboratively with other Scientists, postdoctoral fellows and students in laboratory.

Some examples of techniques that our laboratory routine performs include proliferation, survival, invasion, and apoptosis assays, kinase assays, ELISAs, qPCR, western blotting, cell culture, transfection, gene silencing, lentiviral infection, animal studies using xenograft, syngeneic, GEM, and PDOX models, immune monitoring, NextGen sequencing, single-cell RNAseq, etc.

Experience with mouse models

PhD in chemistry or biology related field and two years experience preferred.

We value the well-being of each of our employees and are dedicated to creating a healthy place for everyone to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors, the University of Kentucky is a Tobacco & Drug Free campus.

The University follows both the federal and state Constitutions as well as all applicable federal and state laws on nondiscrimination. The University provides equal opportunities for qualified persons in all aspects of institutional operations and does not discriminate on the basis of race, color, national origin, ethnic origin, religion, creed, age, physical or mental disability, veteran status, uniformed service, political belief, sex, sexual orientation, gender identity, gender expression, pregnancy, marital status, genetic information or social or economic status.

Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.