Medical Director/Senior Medical Director, Clinical Development in United States at Jobgether

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Medical Director/Senior Medical Director, Clinical Development in the United States.

This role offers a high-impact opportunity to contribute to the clinical development of innovative oncology therapies, with a focus on AML and T-cell engager programs. You will serve as a key clinical leader within a cross-functional development team, shaping study strategy, guiding execution, and ensuring the integrity of clinical data across all trial phases. The position requires strong medical expertise combined with the ability to operate independently in a fast-paced biotech environment. You will collaborate closely with scientific, regulatory, and operational stakeholders to advance novel treatments with the potential to redefine standards of care. This is a highly visible role where your clinical judgment directly influences development decisions, regulatory interactions, and external scientific communication. The environment is collaborative, science-driven, and centered on innovation in oncology and autoimmune disease research.

In this role, you will act as a medical leader across clinical studies, ensuring scientific rigor, patient safety, and high-quality execution of clinical development programs. You will contribute to study design, medical monitoring, regulatory documentation, and cross-functional collaboration across the organization.

• Serve as medical monitor for clinical trials, providing oversight of patient safety, study conduct, and issue resolution.
• Contribute to study design, protocol development, feasibility assessments, and site selection in collaboration with clinical and operational teams.
• Review and provide expert input on clinical study documents, including protocols, informed consent forms, safety plans, and monitoring charters.
• Partner with regulatory affairs to support investigator brochures, briefing documents, and regulatory submissions.
• Lead investigator meetings, support site initiation visits, and maintain relationships with clinical trial investigators.
• Collaborate with data management, biostatistics, pharmacovigilance, and translational teams to analyze and interpret clinical safety and efficacy data.
• Support publication strategy, scientific communications, and presentation of clinical data at internal and external forums.

The ideal candidate brings strong clinical and scientific expertise in oncology drug development, combined with hands-on experience in clinical trial leadership and medical monitoring within biotech or pharma environments. You are confident making independent decisions and collaborating across multidisciplinary teams.

• MD, DO, or equivalent medical degree with board certification or strong clinical background in hematology, oncology, or hematology-oncology.
• 3–5+ years of experience in clinical research within biotech, pharma, or academic clinical trial leadership (Senior level requires broader program ownership).
• Experience in oncology drug development, clinical trial design, and interpretation of safety and efficacy data.
• Strong understanding of Good Clinical Practice (GCP), regulatory requirements, and clinical development processes.
• Experience working cross-functionally with regulatory, clinical operations, pharmacovigilance, and scientific teams.
• Strong communication skills with the ability to clearly present clinical data and medical rationale.
• Ability to work independently, prioritize effectively, and make timely clinical decisions in a fast-paced environment.
• Preferred: experience in AML, leukemias, or myeloid malignancies, and familiarity with T-cell engagers, bispecific antibodies, or immune effector therapies.

• Competitive base salary ranging from $300,000 to $390,000
• Annual performance bonus opportunity (up to 25%)
• Annual equity awards and stock-based compensation
• Comprehensive medical, dental, vision, life, and disability insurance
• 401(k) plan with employer match
• Employee stock purchase plan
• Flexible paid time off, holidays, and end-of-year company shutdown
• Remote or hybrid work flexibility depending on location and role requirements
• Cell phone reimbursement and tuition reimbursement programs
• Paid parental leave and family support benefits