Scientific Director | tRNA Biotherapeutics in Germany at Jobgether
NewJob Function: Science
Jobgether
Germany, Germany
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Job Description
Scientific Director | tRNA Biotherapeutics
Accountabilities:
This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Scientific Director | tRNA Biotherapeutics in Germany.
This is a unique opportunity to lead the scientific vision of a cutting-edge biotechnology platform focused on advancing tRNA-based therapeutics for rare genetic diseases. In this highly strategic and hands-on role, you will guide translational research efforts from early discovery through preclinical development and toward IND readiness. Working at the intersection of RNA biology, gene therapy, and clinical innovation, you will collaborate with global scientific partners and cross-functional stakeholders to shape breakthrough therapies with real patient impact. The environment is entrepreneurial, mission-driven, and deeply collaborative, offering significant influence over scientific direction, platform evolution, and long-term company growth. This role is ideal for a visionary scientific leader excited by innovation, translational medicine, and the opportunity to help define the future of RNA therapeutics.
- Lead and execute the scientific strategy and R&D roadmap across preclinical and translational programs, aligning research activities with key development milestones and long-term company objectives.
- Drive the advancement and optimization of tRNA therapeutic platforms, including elevation and suppression modalities, while translating emerging RNA science into clinically relevant applications.
- Oversee preclinical development activities, including in vitro and in vivo studies, biomarker strategies, delivery technologies, vector optimization, and IND-enabling programs.
- Collaborate cross-functionally with regulatory, manufacturing, clinical, business development, and IP teams to ensure scientific execution supports operational and corporate goals.
- Build and maintain relationships with academic collaborators, scientific advisors, investors, and industry experts while representing scientific progress at conferences and strategic meetings.
- Contribute to company growth through scientific leadership, fundraising support, publication strategy, partnership development, and the long-term development of a high-performing R&D organization.
- PhD or equivalent degree in Molecular Biology, Genetics, Neuroscience, or a related scientific discipline.
- 8+ years of experience in biotech or pharmaceutical environments, including leadership responsibilities within translational or preclinical research programs.
- Strong expertise in RNA biology, translational mechanisms, gene therapy, and AAV-based delivery systems.
- Proven experience advancing therapeutic programs toward IND-enabling studies, including toxicology, biodistribution, dose optimization, and biomarker development.
- Hands-on knowledge of vector engineering, delivery modalities, molecular assays, and preclinical disease models; NHP experience is considered a plus.
- Demonstrated ability to lead cross-functional initiatives in startup or high-growth environments with strong strategic and operational execution skills.
- Excellent communication, stakeholder management, and scientific presentation abilities, with experience engaging investors, collaborators, and advisory boards preferred.
- Entrepreneurial mindset with the ability to balance scientific rigor, innovation, and fast-paced decision-making.
- Opportunity to shape a pioneering therapeutic platform focused on transformative treatments for rare diseases.
- High-impact leadership role with clear progression toward executive scientific leadership responsibilities.
- Flexible remote working model with international scientific collaboration across Europe and beyond.
- Exposure to cutting-edge RNA therapeutics, gene therapy innovation, and translational medicine programs.
- Collaborative environment alongside experienced biotech entrepreneurs, researchers, and global scientific partners.
- Equity-based compensation package with long-term growth potential and participation in company development.
- Meaningful work focused on addressing significant unmet patient needs through breakthrough science.
How Jobgether works:
We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.
We appreciate your interest and wish you the best!
Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.
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Job Location
Germany, Germany
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