Scientist, Lipid Nanoparticle Formulation at Beyond Therapeutics Inc – San Diego, California

We are seeking an experienced Lipid Nanoparticle (LNP) Formulation Scientist to drive the design, execution, and analysis of Design of Experiments (DOE) to establish cutting-edge next-generation LNP platforms focusing on different disease areas. This role will play a critical part in developing, optimizing, and characterizing LNP systems for nucleic acid delivery in a fast-paced, collaborative research environment.

Key responsibilities
• Design, execute, and analyze DOE-based formulation experiments to develop and optimize novel LNP formulations
• Lead formulation innovation efforts, including lipid selection, composition optimization, and novel process development
• Perform LNP screening and characterization, including size, PDI, encapsulation efficiency, stability, and performance metrics

• Lead formulation process scale-up and technology transfer as needed
• Collaborate closely with cross-functional teams (biology, analytics, chemistry, and project management) to advance programs
• Maintain thorough experimental documentation and clearly communicate results and recommendations to stakeholders
• Contribute to troubleshooting formulation challenges and continuously improve experimental workflows
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Professional experience and qualifications
•Scientist, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 2+ years relevant experience; OR M.S. with 3+ years; OR B.S. with 5+ years

•Associate scientist, M.S. in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 1+ years relevant experience; OR B.S. with 3+ years

• Strong hands-on experience with LNP formulations, including formulation development and optimization, process development and scaling-up
• Demonstrated expertise in DOE methodologies and statistical experimental design
• Extensive experience with LNP screening and analytical techniques (e.g., DLS, encapsulation assays, stability studies, physicochemical characterization)
• Deep understanding of lipid-based delivery systems and formulation science principles
• Proven ability to work effectively in a team-oriented, fast-paced environment
• Strong problem-solving skills and ability to manage multiple priorities simultaneously
• Strong communication skills for presenting data and influencing technical decisions

What We Offer
• Opportunity to work at the forefront of LNP formulation innovation
• Collaborative, science-driven culture with high impact research
• Competitive compensation and benefits package, including health, dental, vision, and life insurance

• 401(k) with company match