Clinical Trial Manager/ Senior Clinical Trial Manager in United States at Jobgether
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Job Description
This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Clinical Trial Manager / Senior Clinical Trial Manager based in the United States.
This role is a pivotal leadership position within clinical operations, responsible for driving the successful execution of complex clinical trials from start-up through close-out. You will oversee study operations, ensuring compliance with ICH-GCP, regulatory requirements, and internal quality standards while maintaining strong alignment across cross-functional stakeholders. Acting as the operational backbone of assigned studies, you will coordinate activities across clinical, regulatory, data management, and vendor teams to ensure timelines, budgets, and quality expectations are consistently met. The position requires a hands-on leader who can balance strategic oversight with detailed execution, particularly in managing site relationships, recruitment strategies, and study deliverables. You will play a central role in ensuring data integrity, patient safety, and operational efficiency across global or multi-site clinical programs. This is a highly collaborative and fast-paced environment where your leadership directly impacts study success and overall program delivery.
- Serve as the primary operational lead for assigned clinical trials, overseeing planning, execution, and close-out activities in alignment with protocols and regulatory standards
- Act as the main point of contact for clients, investigators, and cross-functional study stakeholders
- Develop and maintain key clinical study documents including protocols, informed consent forms, monitoring plans, CRFs, training materials, and study trackers
- Lead site feasibility, selection, and recruitment strategy development to support enrollment targets and retention goals
- Oversee study start-up activities including submissions to IRBs/ethics committees and regulatory authorities in collaboration with regulatory teams
- Coordinate cross-functional collaboration with CRAs, data management, programming, QA, and vendors to ensure study alignment and data quality
- Lead internal study meetings, set team expectations, and ensure accountability for timelines, deliverables, and quality standards
- Monitor study performance using metrics and reporting tools, proactively identifying risks and implementing corrective actions when needed
- Oversee investigational product (IP) management, drug accountability, and reconciliation processes
- Support audit and inspection readiness, including CAPA development and implementation
- Manage communication with sites and internal teams to resolve issues, escalate risks, and ensure operational continuity
- May contribute to budget oversight, vendor management, and contract negotiations in collaboration with project leadership
- May assume project management responsibilities when required, depending on program structure
- Bachelor’s degree in life sciences, health-related field, or equivalent combination of education and clinical research experience (advanced degree preferred)
- Minimum of 7+ years of clinical research experience with significant clinical trial management or monitoring exposure
- Strong knowledge of ICH-GCP guidelines, regulatory requirements, and clinical trial operations
- Proven ability to lead cross-functional teams and manage complex clinical studies in pharmaceutical or device research environments
- Experience with clinical trial planning, risk management, and vendor/stakeholder coordination
- Strong leadership skills with demonstrated ability to guide teams, delegate effectively, and drive accountability
- Excellent communication, negotiation, and interpersonal skills in a global, matrixed environment
- Strong analytical thinking, problem-solving, and decision-making capabilities
- Proficiency with standard office tools (Excel, Word, PowerPoint, Outlook) and clinical trial management systems
- Ability to travel domestically and internationally as required
- Competitive salary range of approximately $110,700 to $200,900 USD, depending on experience and location
- Eligibility for annual discretionary bonus and performance-based compensation programs
- Comprehensive benefits including medical, dental, vision, life, and disability insurance
- Retirement savings plan with additional financial wellness options
- Paid time off including vacation, sick leave, holidays, and parental leave support
- Employee wellness programs and health-focused initiatives
- Opportunity to work on innovative clinical trials with meaningful impact in healthcare and patient outcomes
- Professional growth within a globally connected clinical research organization
- Exposure to cross-functional leadership and advanced clinical development practices.