Research Scientist in Pittsburgh, Pennsylvania at University of Pittsburgh

Research Scientist

Med-Medicine - Pennsylvania-Pittsburgh - (26004131)

Overall Lab Summary

Our research group operates at the intersection of computational biology, systems medicine, and translational science within the Vascular Medicine Institute (VMI). We focus on integrating large-scale omics data with mechanistic modeling to uncover systemic drivers of disease. This project provides a unique opportunity to work on NASA spaceflight data while developing broadly applicable frameworks for understanding organ dysfunction and therapeutic intervention.

Job Duties

• Integrate and analyze multi-modal transcriptomic datasets (bulk RNA-seq, single-cell RNA-seq, spatial transcriptomics, and time-series data).

• Identify disease molecular signatures under spaceflight and simulated conditions.

• Construct and analyze gene regulatory networks (GRNs) to infer upstream regulators.

• Develop and apply deep learning–based drug repurposing approaches to identify compounds that reverse space flight-induced regulatory disruptions.

Job Summary

Conducts independent scientific research projects from inception to presentation. Prepares and crafts various documentations of research results into manuscripts, proposals, grant applications, and presentations. Trains undergraduates and research technicians. Manages laboratory policies and coordinates project development in collaboration with other specialists.

Essential Functions

• PhD-level knowledge in computational biology, bioinformatics, systems biology, data science, or a related field.

• Strong experience in transcriptomic data analysis, experience with spatial transcriptomics is a plus.

• Demonstrated expertise in statistical learning or machine learning.

• Experience with network biology, pathway analysis, or gene regulatory network inference.

• Ability to work independently on complex, interdisciplinary projects.

Physical Effort

Position is hybrid. Must be able to move between VMI offices and labs as needed. Most sedentary.

Assignment Category: Full-time regular

Job Classification: Staff.Research Scientist

Job Family: Research

Job Sub Family: Research Science

Campus: Pittsburgh

Minimum Education Level Required: Professional Doctorate Degree

Minimum Years of Experience Required: 5

Will this position accept substitution in lieu of education or experience: No

Work Schedule: mon-friday standard

Work Arrangement: Hybrid: Combination of On-Campus and Remote work as determined by the department.

Hiring Range: To be determined based on qualifications

Relocation_Offered: No

Visa Sponsorship Provided: No

Background Check: For position finalists, employment with the University will require successful completion of a background check

Child Protection Clearances: Not Applicable

Required Documents: Resume

Optional Documents: Not Applicable