Senior Manager / Associate Director, Gross-to-Net & Revenue Planning in Menlo Park, California at Orca Bio
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Job Description
Position Summary: The Senior Manager / Associate Director, Gross-to-Net (GTN) & Revenue Planning will own gross-to-net, revenue forecasting, and commercial operating expense forecasting for Orca Bio's first commercial product. Reporting to the Senior Director/Head, FP&A, this role establishes the accrual methodology, forecast architecture, documentation, and monthly cadence that a newly commercial company requires — in a product setting where individual transactions are material and where there is limited precedent to inherit. The position requires strong technical judgment, cross-functional partnership, and deep expertise in pharmaceutical revenue deductions and government pricing.
This is a hands-on individual contributor role. The successful candidate will build the models, run the monthly process, reconcile the underlying data, and present results directly to executive leadership and external auditors.
Cross-Functional Ownership & Key Interactions
This role carries broader ownership of the gross-to-net cycle than a typical FP&A revenue position — performing the methodology, calculation, and reconciliation work for activities that are often split into Accounting — while Controllership retains accountability for the close and Market Access owns contracting.
Gross-to-Net Accounting & Analysis
- Own the monthly and quarterly gross-to-net accrual and reserve process end to end, including distribution and title fees, specialty pharmacy fees and prompt-pay discounts, Medicaid rebates, 340B, FSS/VA pricing, chargebacks, and other revenue deductions as the channel develops
- Establish and maintain accrual rate methodology and assumption documentation for a newly launched product with limited claims history
- Execute rate true-ups as actual claims and utilization data mature, and explain the resulting variances
- Build and maintain reserve roll-forwards, reserve-to-payment reconciliations, and rate variance analyses
- Serve as the finance owner of third-party government pricing calculations — AMP, Best Price, non-FAMP, Medicaid unit rebate amount, and 340B ceiling price — validating vendor output in partnership with Market Access and supporting executive certification
- Monitor payer mix, channel dynamics, and reimbursement developments, and translate them into forecast and reserve implications
Revenue Forecasting & Analysis
- Partner with Commercial Operations & Strategy on the revenue forecast build, from treatment-center-level demand through gross sales to net revenue
- Support the modeling of drivers specific to cell therapy, including authorized treatment center activation and ramp, referral-to-infusion conversion, manufacturing capacity and slot constraints, donor eligibility yield, and vein-to-vein timing
- Work with Commercial Operations & Strategy to deliver the monthly latest estimate, quarterly reforecast, annual budget, and long-range plan inputs for revenue and gross-to-net
- Produce variance analysis and written commentary for executives and Board reporting
- Partner with Commercial and Market Access to align demand assumptions with field intelligence and account activation plans
Commercial Operating Expense Planning
- Partner with Commercial, Market Access, Patient Services, and Medical Affairs on budget, latest estimate, and long-range planning for commercial operating expenses
- Own budget-versus-actual reporting, accrual review, and variance commentary for commercial functions
- Track headcount and program spend against plan, and support functional leaders in managing their budgets
Financial Reporting & Compliance
- Partner with Accounting on the revenue close, including journal entries, account reconciliations, flux analysis, and cut-off
- Ensure compliance with GAAP, ASC 606, SOX (as applicable), and internal controls
- Build and maintain audit-ready documentation and control narratives for gross-to-net and revenue processes
- Serve as a primary point of contact for external auditors on gross-to-net methodology and revenue forecasting assumptions
- Contribute analysis and peer benchmarking to technical accounting positions on revenue deductions and other ASC 606 matters
Systems, Data & Process Scale
- Own the flow of finance data from third-party logistics, specialty pharmacy, and distribution partners into forecast and accrual models
- Support implementation and maintenance of ERP and planning systems as they relate to revenue and gross-to-net
- Drive automation and reporting improvements as transaction volume grows
- Support gross-to-net and revenue process design for ex-US markets as they are added
• 7+ years of progressive biopharmaceutical finance experience, including direct, hands-on ownership of gross-to-net
• Demonstrated experience building gross-to-net accrual methodology from first principles, rather than solely operating an established revenue management system
• Strong understanding of US GAAP and ASC 606 as applied to pharmaceutical revenue and revenue deductions
• Working knowledge of US government pricing programs — Medicaid, 340B, FSS/VA — and how they interact with commercial channel terms
• Experience partnering across Accounting, Market Access, Commercial, and external auditors
• Strong analytical and problem-solving skills, with sound judgment in the absence of established precedent
• High attention to detail and accuracy and ability to manage multiple priorities in a fast-paced environment
$155,000 - $200,000 a year