Senior Director, Commercial Operations at Larimar Therapeutics – Philadelphia, Pennsylvania

The Company:

Larimar Therapeutics Inc. is a publicly held clinical-stage biotechnology company focused on developing treatments for patients suffering from complex rare diseases using its novel cell penetrating peptide technology platform. Our lead product candidate, Nomlabofusp (CTI-1601), is a subcutaneously administered, recombinant fusion protein intended to deliver human frataxin (FXN), an essential protein to the mitochondria of patients with Friedreich’s ataxia. Friedreich’s ataxia is a rare, progressive, and fatal disease in which patients are unable to produce sufficient FXN due to a genetic abnormality.

We have assembled an experienced management team, each of whom has over 20 years of pharmaceutical industry experience. Our management team, employees, and consultants have significant expertise in discovery, nonclinical and clinical development, regulatory affairs, manufacturing and CMC.

Our company’s strategy is to become a leader in the treatment of rare diseases by leveraging our cell-penetrating technology platform and applying our team’s know-how to the development of Nomlabofusp and our pipeline projects. We are best characterized by entrepreneurial and scientific leadership and a participatory workforce committed to success.

Position Overview:

The Senior Director, Commercial Operations will serve as a strategic leader responsible for driving commercial and operational excellence across the organization. This role will collaborate cross-functionally to establish and implement best practices, methodologies, and processes that enable efficient and effective commercial execution.

The Senior Director will oversee the design, development, and maintenance of commercial systems, forecasting frameworks, policies, and governance documents to support both the launch and ongoing commercialization of nomlabofusp. Key responsibilities include the automation and delivery of weekly performance reports and insights, as well as the co-design and administration of sales force incentive compensation programs in close partnership with Sales Leadership.

In collaboration with the Information Technology team, this leader will identify, develop, and deploy enterprise platforms and technology solutions to enhance operational efficiency, optimize access to patient-level and performance data, and ensure seamless integration across systems. The role will also manage key third-party partnerships, including customer relationship management (CRM) providers and data aggregators, to ensure robust data integrity and alignment with strategic objectives.

Key Responsibilities:

Forecasting

• Partner with Commercial and Finance teams to develop, analyze, and communicate commercial program budgets, ensuring accurate and timely forecast reporting.
• Lead the development and delivery of daily and weekly product revenue reports in collaboration with Finance.
• Support monthly and quarterly revenue forecasting processes, ensuring alignment with strategic and financial objectives.

Business Intelligence and Analytics

• Collaborate with Commercial stakeholders to design, implement, and maintain technology and analytics solutions that align with the organization’s strategic direction.
• Partner with cross-functional teams to identify and prioritize high-impact insights across key business areas, including Sales, Medical Affairs, Marketing, Finance, Market Access, Patient Services, and IT.
• Develop and validate dynamic dashboards and analytical tools to integrate and interpret diverse data sources, driving actionable business outcomes.
• Establish data governance and reporting standards to ensure accuracy, consistency, and responsiveness for executive-level and field-based information requests.

Field Operations

• Lead the design, implementation, and management of the company’s customer relationship management (CRM) system in partnership with Commercial, IT, Quality, and Finance teams.
• Oversee strategic and tactical field planning, including region and territory alignment, vehicle programs, incentive compensation design and administration, data management, reporting, and CRM optimization.
• Manage data inquiry processes and stewardship initiatives to ensure data integrity and support field team effectiveness.

Trade Relations

• Collaborate with Manufacturing, Supply Chain & Quality to ensure seamless integration between manufacturing and distribution operations.
• Partner with Market Access and Finance to support Commercial objectives related to Gross-to-Net calculations, inventory management, chargebacks, and product returns.

Additional Responsibilities

• Partner with IT to define and advance Larimar’s enterprise data strategy.
• Perform additional duties and strategic initiatives assigned by the VP, Commercial.

Qualifications:

Experience

• Minimum of 10 years of experience in the pharmaceutical or biotechnology industry, with a focus on Commercial Operations, Business Intelligence, or Analytics.
• Bachelor’s degree in Business, Data Analytics, or a related field; equivalent relevant experience will be considered.
• Demonstrated expertise in forecasting, data management, and commercial analytics.
• Strong verbal and written communication skills, with proven organizational, time management, and project management capabilities.
• Experience within the rare disease sector preferred.

Vision and Adaptability

• Proven ability to operate in a startup environment with a ‘self-starter’ mentality.
• Energized by the opportunity and the need to ‘build it ourselves.’
• Driven to get it done for the patients who depend on us.

Benefits:

Larimar Therapeutics offers all employees incentive stock options, a comprehensive benefits plan including 401K, and a flexible PTO policy.

We are committed to equal-employment principles, and we recognize the value of committed employees who feel they are being treated in an equitable and professional manner. We strive to find ways to attract, develop and retain the talent needed to meet business objectives, and to recruit and employ highly qualified individuals representing the diverse communities in which we live.

Employment policies and decisions on employment and promotion are based on merit, qualifications, performance, and business needs. The decisions and criteria governing the relationship with all candidates and employees are made in a non-discriminatory manner—without regard to age, race, color, national origin, gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), gender identity or expression, religion, physical or mental disability, medical condition, legally protected genetic information, marital status, veteran status, military status, sexual orientation, or any other factor determined to be an unlawful basis for such decisions by federal, state, or local statutes.