Principal Architect - ECD at Jobgether – United States

Principal Architect - ECD

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Principal Architect - ECD in United States.This is a strategic and highly visible role for an experienced architect to lead the design and evolution of high-scale, cloud-native systems for early cancer detection technologies. You will define architectural patterns, guide platform strategy, and ensure robust, modular, and scalable systems that drive innovation in a mission-critical environment. The role requires collaboration across engineering, product, AI/ML, and operations teams to shape technical direction, implement modernization initiatives, and integrate intelligent services. You will mentor senior engineers, enforce architectural governance, and make hands-on contributions to complex system design. The position combines technical vision, strategic thinking, and practical execution in a dynamic, innovation-driven environment.Accountabilities:

• Define and own the architectural strategy for high-scale, cloud-native systems, aligning technology with long-term business objectives.
• Design and evolve enterprise systems emphasizing scalability, maintainability, observability, and security.
• Create architectural blueprints, reusable frameworks, and standards to guide engineering teams in developing high-performance services and applications.
• Act as a technical thought partner across engineering leadership, product managers, and executive stakeholders, providing mentorship and cultivating a culture of architectural excellence.
• Lead modernization initiatives, including migration to service-oriented or event-driven architectures, and introduce emerging technologies to improve system resilience and developer productivity.
• Partner with AI/ML teams to integrate intelligent services and real-time analytics at scale.
• Maintain a system-level view to anticipate bottlenecks, manage risk, and provide guidance for hands-on solution design and technical troubleshooting.

Requirements:

• 12+ years of professional software engineering experience, with at least 6 years in a senior architectural leadership role.
• Proven expertise in designing and scaling enterprise software systems, preferably in cloud-native environments (AWS preferred).
• Experience leading architectural transformation initiatives, including service decomposition, domain-driven design, and platform re-architecture.
• Strong understanding of architectural trade-offs including performance, resilience, cost, and security.
• Excellent communication skills with the ability to explain complex technical concepts to both technical and non-technical stakeholders.
• Preferred experience in scientific, healthcare, or lab operations domains, including familiarity with LIMS/LES systems and regulated software environments.
• Strategic thinker with strong leadership skills grounded in empathy, curiosity, and impact.

Benefits:

• Competitive base salary ($182,900$228,600 USD) with potential additional performance incentives
• Long-term equity awards
• Comprehensive health benefits including medical, dental, and vision coverage
• 401(k) plan with company match
• Generous paid time off and company holidays
• Additional wellness and work-life benefits

Why Apply Through Jobgether?We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.We appreciate your interest and wish you the best! Why Apply Through Jobgether?
Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.

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