Director/Senior Director, Site Excellence at Jobgether – United States

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Director/Senior Director, Site Excellence in the United States.

This role is a senior leadership position responsible for defining and executing the strategy, operational models, and performance standards for specialized and partner-operated clinical research sites across the United States. The Director/Senior Director will balance high-level strategic planning with hands-on operational oversight, ensuring site excellence while scaling processes and frameworks. You will lead initiatives across site startup, enrollment, quality, and partner engagement, while acting as a key escalation point for complex operational and regulatory challenges. The position requires strong collaboration with cross-functional teams, driving consistent execution across a portfolio of sites. This is an opportunity to shape scalable, high-performing clinical site operations that directly impact healthcare delivery and research outcomes.

• Lead the strategy, design, and execution of operating models for specialized and partner-operated clinical research sites.
• Build and embed operational excellence frameworks, KPIs, dashboards, and review cadences to monitor performance across quality, enrollment, timelines, cost, and patient experience.
• Personally drive critical initiatives until stable, scalable, and ready for delegation, acting as a senior escalation point for operational, regulatory, and partner-related issues.
• Manage end-to-end site startup, onboarding, and integration for new site models, ensuring alignment with protocol, sponsor, and regulatory requirements.
• Oversee quality, compliance, and risk management, including audit readiness and corrective/preventive action plans.
• Own financial and business performance for specialized and partner site portfolios, partnering with Finance to build budgets, forecasts, and optimize margins.
• Build and lead a high-performing leadership team, establishing role clarity, decision rights, and coaching for proactive, scalable execution.

Requirements:

• Bachelor’s degree required; advanced degree (MBA, MPH, MS, or similar) strongly preferred.
• 12–15+ years of progressive leadership experience in clinical research operations, site management, or healthcare services.
• Demonstrated success in building and scaling non-traditional, partner-led, or complex site operating models.
• Deep understanding of site-level execution, including startup, enrollment, regulatory processes, sponsor engagement, and remediation.
• Strong knowledge of FDA regulations, GCP, and clinical trial operations.
• P&L ownership experience across multi-site portfolios.
• Proven ability to operate as both a strategist and hands-on operator in high-growth or ambiguous environments.
• Exceptional executive communication, stakeholder influence, and change management skills.
• Preferred: Experience with decentralized or innovative clinical trial delivery models and operating in matrixed, global organizations.

Benefits:

• Competitive base salary ($130,000 - $190,000 USD annually) plus discretionary annual bonus.
• Paid Time Off (PTO) and company-paid holidays.
• 100% employer-paid medical, dental, and vision insurance plan options.
• Health Savings Account (HSA) and Flexible Spending Account (FSA) with bi-weekly employer contributions.
• Company-paid Short-Term Disability and Long-Term Disability.
• 401(k) retirement plan with company match.
• Remote work within the United States with up to 70% travel, providing flexibility and autonomy.
• Opportunities for career growth and leadership development in a mission-driven environment.