Manager, Operational Excellence & OEE Lead at Jobgether – United States

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Manager, Operational Excellence & OEE Lead in the United States.

This role sits at the intersection of operational strategy, life sciences execution, and continuous improvement leadership, driving measurable performance gains across complex biopharmaceutical environments. You will lead Operational Excellence and Overall Equipment Effectiveness (OEE) initiatives that directly impact project delivery, manufacturing efficiency, and client outcomes. Acting as both a subject matter expert and team leader, you will guide cross-functional teams in applying Lean, Six Sigma, and other improvement methodologies to real-world operational challenges. The position combines hands-on client engagement with strategic program leadership, ensuring scalable and sustainable performance improvements. You will also play a key role in mentoring teams, embedding best practices, and strengthening standardized work systems across client organizations. This is a high-impact consulting leadership role where your expertise directly contributes to improving the delivery of life-changing therapies.

• Lead the design, development, and execution of Operational Excellence and OEE strategies, including assessments and implementation roadmaps across client engagements.
• Serve as a subject matter expert in Lean, Six Sigma, Kaizen, DMAIC, Value Stream Mapping, Gemba, and 5S methodologies, guiding their application in client environments.
• Coach and mentor cross-functional teams in the practical use of OpEx and OEE tools to drive measurable performance improvements.
• Oversee KPI development, tracking, and performance management to ensure alignment with business objectives and operational targets.
• Lead cross-functional teams across Engineering, Operations, Quality, and Supply Chain in biopharmaceutical manufacturing environments.
• Embed continuous improvement practices into standardized work processes and ensure long-term sustainability of improvements.
• Develop and implement visual management systems to support operational transparency and performance tracking.
• Drive identification and execution of tangible business improvements across cost, quality, schedule, and productivity metrics.
• Act as a client-facing leader, influencing stakeholders and supporting decision-making in complex and ambiguous environments.

• Bachelor’s or Master’s degree in Engineering, Life Sciences, Regulatory, or related field, or equivalent relevant experience.
• 8–14+ years of experience in Operational Excellence, consulting, or manufacturing/biopharmaceutical environments.
• 7+ years of experience working in GMP-regulated environments, preferably within drug substance, drug product, or packaging operations.
• Strong expertise in Lean, Six Sigma, Kaizen, DMAIC, VSM, Gemba, 5S, and related continuous improvement methodologies.
• Proven experience leading OpEx and OEE programs and delivering measurable, data-driven business outcomes.
• Demonstrated ability to lead large cross-functional teams (10–20 members) in complex operational settings.
• Strong leadership, coaching, and mentoring capabilities with experience developing team performance.
• Ability to define and manage KPIs, performance systems, and structured improvement frameworks.
• Experience working in consulting or client-facing environments, ideally within life sciences or manufacturing.
• Black Belt certification in Lean Six Sigma or equivalent preferred.
• Strong communication, stakeholder management, and influence skills in dynamic and ambiguous environments.

• Competitive annual salary ranging from $110,000 to $155,000, based on experience and location.
• Comprehensive health benefits including medical, dental, and vision coverage.
• Retirement savings plans and financial wellbeing support programs.
• Paid time off and flexible work arrangements supporting work-life balance.
• Opportunities to work on high-impact biopharmaceutical projects improving patient outcomes.
• Strong professional development, mentoring, and leadership growth opportunities.
• Inclusive, collaborative, and mission-driven work culture focused on continuous improvement.
• Exposure to advanced Operational Excellence frameworks and industry-leading consulting practices.